All of Us study finds thousands of new genetic variants affecting drug responses.

The Kremlin can hide the death toll. It can’t hide the graves.

AI pioneer Yoshua Bengio implores Europe to build frontier models. Will never happen.

The amazing disappearing exoplanet.

The Jensen Huang scandal is hardly over.

A Natural Gas Project Off Alaska’s Coast May Be a Russian Ploy for Intel on the Arctic.

How Trump’s War on Offshore Wind Upended a “Limitless” Future for Thousands of New England Workers.

Synaptics patent claims stop work on DisplayLink drivers. Evil. Fuck them.

AMD’s Zen 6 Family: Feeding the Beast.

‘Fjord,’ and the Paradox of Tolerance.

Google DeepMind just mathematically verified key parts of Signal.

The US military seems to be getting nervous about the launch supply crunch.

Rich Country, Poor Citizens: China’s $20 Trillion Paradox.

10-Year Treasury Yield Spikes as Inflation Spreads across Economy, Driven by Ugly Core Services CPI.

Nvidia Is Preparing to Oust CEO Jensen Huang.

An American Furniture Maker Tried to Bring Jobs Back Home. It Didn’t Work.

Nvidia’s Disappearing Singapore Sales Deepen Mystery Around Megaspeed.

The Fridge-Hacking Spree Is an Internet-of-Things Wake-Up Call.

Sacred Cows Are Made to Be Kicked. Dave Chappelle, Charlie Kirk and why and when transgressive humour thrives.

He was diagnosed with cancer. Then he was told he lost his Medicaid.

California voters defeat billionaire tax proposal that divided Democrats.

Trump Admin Caught Illegally Canceling Billion-Dollar Solar Project That Would Have Helped Lower Utility Bills Across the Country.

High oil prices have led to a dip in global carbon emissions.

Ukraine’s fiber-optic drones get squeezed by AI data center demand.

Global warming near levels forecast for 2040: UVic study.

LLM as Interface.

Scion Is Back! And It’s Going To Sell A Freaking Kei Truck In America.

Smart home devices should work without the internet.

To deter bioterrorism, U.S. imposes new rules on ordering synthetic DNA.

The History of GeoWorks, Microsoft Windows’ Upstart ’90s Competitor.

Nvidia opens investigation after reports CEO Jensen Huang was targeted by Chinese intelligence.

NATO faces €7B shortfall on military aid pledge to Ukraine.

I’m Not Convinced The AI Bubble Exists. Agreed.

A desert stirs to life: Chile’s Atacama erupts in its biggest floral display in decades.

Perhaps Connecting Fridges to the Internet Was a Bad Idea.

Your phone number is now tied to all your Google accounts, and you never agreed to it.

Social Security Deficit Blows Out: Trust Fund, Income, Costs, Deficits, and Interest Rates in Fiscal 2026.

Locating the source of a mysterious beep with Claude.

Magenta solar panels may be agrivoltaics’ cleverest trick yet.

Google Gemini routes personal Drive files and emails to human annotators.

Sodium-ion batteries approach cost parity with LFP, with 70 GWh covered by supply agreements.

Ozempic-style drugs are now in trials for heart failure, addiction and even aging.

The Education a STEM Major Needs. “Great Books” courses won’t teach students the meaning of life—but they can help them think about it.

Flouting Consumer Law, Insurers Refuse to Pay Medical Bills for Emergency Care.

Every Windows 11 app should kill Electron, and Discord just showed why: no “Starting” screen and 70% less RAM, even with two accounts signed in.

Theory predicting an older universe without dark matter or dark energy passes key cosmological tests.

Struggling to spell ‘male chauvinist pig’? Apple’s grey list means your iPhone won’t help you. In Australia, but sure similar is true elsewhere. Also, pure evil.

In defense of feral children.

The highest IQ populations today are both not reproducing but also replacing themselves with low IQ populations.

Every Mac since 2022 ships a pair of daemons whose only purpose in life is to build a graph about you and the people around you: who you are, who you know, how those people are related to you and to each other, how you communicate with them, where you go, with whom, what you do and when. Ugh.

Iconoscope.

Facebook knowingly runs AI deepfake scam ads as Meta docs reveal $16 billion in fraud-linked revenue.

You should absolutely download your favourite youtube videos. Piracy is a moral imperative.

A Guide To China’s Expanding Fleet Of Military Helicopters.

No more Cybertrucks; Musk moves on from the angular metallic flop.

Zillow Traffic Slides as High Mortgage Rates Freeze Housing Market.

Generational Wealth Fuels Record-High Levels of Cash Sales Among First-Time Buyers.

A Critical History of the Cost-Benefit State: Part 1.

Earth’s churning mantle may have created the Great Unconformity.

The Blue Wave Has Tech Bros Scrambling for Data Centers in Space.

I Toured Unitree's Factory. I'm More Bullish on the West Than Ever.

US FAA says it will phase out floppy disks from air traffic control by 2028.

AI is dramatically accelerating AI research right now.

Tusk says Poland thwarted possible provocation on Kaliningrad border overnight.

So I guess we don’t have customer service people anymore.

Google Will Turn Off Search for Schools That Reject A.I.

Claude’s new rules against game cloning won’t stop the AI copying boom.

Hedge Fund Elliott Warns of FOGO: Fear of Getting Obliterated in the Market.

Florida Has Become the New Hotbed for Defense Startup Money.

The Price of Ordinary Life: Housing, Essential Services, and the Political Economy of Scarcity.

The onward march of cognitive capitalism.

Europe's Plot To End Americans' Online Anonymity.

Emily Wilson’s “Feminist” Take on The Odyssey.

Rare beetle that oozes substance from its knees when attacked rediscovered in Wales.

Salon is shutting down after 31 years.

What I learned driving the Slate electric truck prototype. After 45 minutes behind the wheel, I am more optimistic about the $25,000 EV.

Normal Americans punished MAGA.

People say they want small smartphones—the Enough Phone will put that to the test.

Insects Don’t Swarm at LED Lights.

AI is forcing us to pay off 40 years of technical debt.

AMD expects to outsell Intel in Q4 for the first time in history.

North Korean fake job interview led to $6.3B Binance heist.

Verification Is Not Knowledge. Science needs more than answers.

I have a close friend who flies private jets. He flew Lear 60 for over 15 years and now flies a Gulfstream.

NASA Announces X-70 “Fractal” Experimental Aircraft.

USAF Widens Lower-Cost Cruise Missile Effort To Also Include Glide Bombs.

Lürou Huoshao.

Disney Eyes Thousands of Job Cuts Amid Cost-Cutting Drive: Managers Given 20% Savings Target.

There Are Now Growing Signs That AI Is Hurting Employment in the Job Market. Duh. Also, told you so.

Giant Canyon on Mars Is Still Tectonically Active Today.

Fujifilm to boost tape production 5x as AI fuels archiving demand.

The Internet’s Conspiracy Theorists Are Desperate for Voter Fraud.

Opioid Users Found a ‘Miracle Drug’ to Help Them Quit. Then the DEA Banned It.

Labor Market Churn Accelerates on Big Jump in Quits.

The Final Seconds Before a Learjet Plunged Into a Florida Street.

CVS Will Break Off Its Namesake Pharmacies.

California’s plastic law will cut far less single-use plastic than expected. Moronic evil fucking worthless law.

No Country for Polite Quitters. The courteous two-week notice is … on notice.

Scientists have what they say is one of the oldest Mars meteorites.

Two economists studied California's billionaire tax. They reached wildly different conclusions.

Googling “Zelda” today offers a glimpse of how search worked in 1998.

Boy Names That Became Girl Names (and Vice Versa).

The SEC Should Block Anthropic’s IPO to Protect the Public.

Anthropic's internal AI use, valued at retail prices, now exceeds its employee pay.

No Inflection Point Yet: Near-Exponential Data Center Boom Sends Shockwaves to Industrial Economy, Construction Hit by 2nd Wave of Inflation.

So when he says cooling in space is "easy", that doesn't mean what normies mean by "easy", which is "doesn't take a lot of resources, time, or expense". Correct.

“At Home in Space” opens, caps Air and Space Museum renovation.

Here’s What the Inca Gave Children Before Sacrificing Them on Volcanoes.

Lawmakers Can’t Ban VPNs No Matter How Hard They Try.

Why Europe doesn’t have a Tesla.

The Midterms Won’t Fix What Ails Consumers.

How Trump Is Dismantling America’s Scientific Research Machine. Long term, this is the worst and most harmful thing Trump is doing. And it’s not even close.

Believing your own propaganda too much is risky even when it's true, and extremely dangerous when it's false.

The 13 AI Giants, from Alphabet to Oracle, Sit on $1.13 Trillion in Cash. They Can Keep Spending on AI even if Markets Get Ugly.

Mystery of 60-Second Fluctuations in Power Grids Solved.

An Italian Farmer Found Some Unknown Seeds in His Attic and, With Nothing to Lose, Planted Them.

AI agent swarms unleashed in Minecraft to ‘build a thriving civilization’ — 50-agent teams fail after falling into paralyzing bureaucracy.

To Tame the Fastest Drivers, States Deploy Speed-Limiting Devices on Cars.

Fine and ultrafine Martian dust presents additional risks for future crewed missions to Mars.

The oldest ice is disappearing: The Stone Age is emerging from the melting ice.

Meta’s Muse AI agent is a commercial surveillance network disguised as an AI assistant.

How Iran Battered U.S. Bases and Caused Billions in Damage.

Christine Lagarde’s Lonely Next Act: Defender of a Fading Globalist Order.

Ukraine Hits Russian Oil Refinery, Ending Pause and Defying Trump. Good.

Unusual quantum states in six-layer graphene offer clues to superconductivity.

Experimental study on moths supports the molecular cookie cutter idea proposed for butterflies.

The US is facing the greatest espionage threat in its history.

OpenAI CEO says it's 'quite terrible' for your PC to have RAM — Sam Altman says data centers offer better utilization. Moron.

Could Europe’s autumn of discontent threaten the survival of the EU?

Supersonic airliner in doubt as company shifts to powering AI data centers.

SpaceX no longer needs NASA, and that’s a problem for America’s space agency.

So, I was severely bullied by a friend group / cult in my early twenties. Two years ago I read the book Odd Girl Out: The Hidden Culture of Aggression in Girls, by Rachel Simmons, and it felt incredibly familiar.

Rare fossil discovery reveals new dinosaur species that specialized in eating fruit.

James Bridle experiments with combining their practical carpentry skills and the abundant theoretical knowledge of AI to build a chair.

Wall Street Is Starting to Call the Shots in America’s AI Build-Out.

Russia’s Shadow Fleet Turns to Nets and Rubber Tires for Makeshift Drone Armor.

At least 900 Flock cameras have been unplugged in Texas since state funding was cut.

Cisco gives 27-year-old engineer unlimited AI tokens to rewrite 98% of the company's legacy code in 24 months — president plucks former startup founder, telling him to 'go nuts.'

CGI Gore Is a Plague on Horror. There May Be a Cure.

Thread on the new soullessness of college neighborhoods.

The case against (extremely fast) RSI. Correct.

A Defense Contractor Gave Their Personal AI Agent Access to a Secure Pentagon System.

Mistral Says Its AI Model ‘Le Chonk’ Has Leapfrogged China in the Open-Weight Race.

Microsoft killed Windows 10 to push Windows 11, but Windows sales crashed 27% as holdouts still refuse to switch.

Inside the U.S. Military’s Open-Ended Mission to Keep Gulf Oil Flowing.

The Cheesecake Factory Is Over-the-Top, Gaudy and Bizarre. That’s the Point.

‘People’s Republic of the Disappeared’: Stories of Horror But Also Resilience.

Thousands of “ghost students” use AI to steal millions in student loans, DOJ says.

General Atomics Developing Strike-Recon Flying Wing Called NextGen That Uses Hybrid-Electric Propulsion.

Japan To Assemble AMRAAM Missiles As U.S. Moves To Dramatically Boost AIM-120 Production.

U.S. Is Missing 4.3 Million Households as Priced-Out Young Adults Stay Home.

Once again, NASA is asking for ideas to rescue Hubble from certain death.

Qwenputer: a fully functioning, deterministic RISC-V CPU inside Qwen3.5.

Confessions Of An SR-71 Blackbird Pilot.

China’s CE-25A Electric Commuter Airliner Demonstrator Emerges.

Police are pulling people over because license plate cameras say their travel patterns look "suspicious."

The Migration Sales Pitch They Never Gave You.

England has developed into a complete dystopian tyranny.

"Mental load" is an interesting example of a slanted idea, designed by absurdly silly activists. making it into normal discourse.

Christine Lagarde to Resign Early as ECB President.

As Missile Stockpiles Dwindle and China Looms, U.S. Turns to Japan for Production.

America's Truckers on the Brink With 221 Bankruptcies This Year.

Belgium restored nuclear power output.

Polish MiG-29s, F-16 Cannon Ammo Reportedly Headed To Ukraine As Bitter Warsaw-Kyiv Rift Heals.

Trump ignored intel on China’s Nvidia spy to protect company’s stock, report says.

What America is Living Without.

The Bigger Meaning Found In Four-Hour Amazon Delivery Times.

China and the US Are Competing for Space Dominance.

They bought cabins to live on a luxury cruise ship. High fuel costs got them kicked off in Cambodia.

Mega and Large Investors Pull Back from Housing Market, Become Net Sellers, Small Investors Continue to Pile In.

Obesity in young adulthood linked to increased risk of early-onset cancer.

We have created a society where the equilibrium solution to the problems presented in life is simply not to pair off.

Women are hilariously deluded about what works on women. This is 100% correct. All men learn this the hard way.

A Punishing Housing Market Is Squeezing Renters.

It Looks Like the Polar Vortex Is About to Do Something ‘Unprecedented’.

One of the greatest museum artifacts ever is at L.A.’s $450 million Air and Space center.

Your fitness today is basically a measure of your ability to regulate yourself and do what is best for your long term well being in spite of everything around trying to crush you.

They Sold Everything to Live on a Cruise Ship. Now They’re Stuck in Cambodia.

The Baby Bust Is Forcing a Reckoning at Public Schools.