Microbial biotherapeutic metabolite alleviates liver injury by restoring hepatic lipid metabolism through PPARฮฑ across the gut-liver axis.

End of US low-value package tariff exemption is permanent, Trump officials say. Clownery.

YFQ-42 โ€˜Fighter Droneโ€™ Collaborative Combat Aircraft Has Flown For The First Time.

Trumpโ€™s funding cuts set back research on important health issues by years, Harvard scientists say.

When bison have room to roam, they reawaken the Yellowstone ecosystem.

Why progressives should care about falling birth rates. Yup.

A.I. Is Coming for Culture.

Mastodon says it doesnโ€™t โ€˜have the meansโ€™ to comply with age verification laws.

The bigger story behind the mass exodus of CDC leadership.

Inco Fact

Yup. The FA movement has always hated this, but the fact is the fitter and the less obese you are prior to surgery the better you do after.

Another inconvenient fact.

Cumen But Not Spicy

Same. And I don’t want to be anyone’s stock picker or be blamed for their (or my own) missteps.

I don’t require anyone’s validation. I own a house free and clear and have a secure1 retirement as a result of my financial acumen. I don’t need to convince a soul. The proof is what I’ve done. If that doesn’t convince you, the depths to which I don’t give a fuck are infinite and unprospected by me.

  1. Unless Trump totally tanks the economy forever, which might happen.

Bankers learn they are fired via accidental email asking them to return laptops.

The booming business of Trumpโ€™s deportation flights.

Why the vegans lost. Could be a short article. Should just say, “Because they were fucking nuts.”

The majority of Canadians that own property in the U.S. plan to sell, survey finds.

Blogging service TypePad is shutting down and taking all blog content with it.

Recently, a woman slowed down a line at the post office, waving her phone at the clerk. ChatGPT told her there’s a “price match promise” on the USPS website. No such promise exists. But she trusted what the AI “knows” more than the postal worker.

Age of Invention: The Century-Long Depression.

There Goes the American Muscle Car.

AI Off

It doesnโ€™t really matter if AI can really do your job or not, itโ€™s so much cheaper they will try it anyway.

Exactly. That’s what so many otherwise smart people do not understand about AI. I am actually not sure how they can be so incredibly naรฏve about how this will work.

In short, it does not matter if an AI can actually do your job. If an MBA thinks they can string together four mediocre to bad AI agents to do your job for 1/20 the cost and 1/4 the quality, that is what is gonna happen.

It’s already happening. Pretending it’s not is just pure clownery.

The Whole Point

This isn’t some slantwise intepretation. This is what the Dune books are about. Frank Herbert was very explicitly exploring how charismatic revolutionaries, even when they start outside the system, tend to reproduce the same oppressive structures they overthrow. That’s, like, the entire point of the whole series.

That’s not being clever, this interpretation. That is just being able to read. Dang.

Despin

The economy is doing very poorly but it takes a while for it to be obvious.

And things are going to get so much worse.

Chinese astronauts make rocket fuel and oxygen in space using 1st-of-its-kind ‘artificial photosynthesis.’

One Universal Antiviral to Rule Them All?

Chinaโ€™s Guowang megaconstellation is more than another version of Starlink.

We now live in a highly polarized country, where even election results are contested. Politicians are cheerleaders, not statesmen. Economic statistics are discussed not in terms of their implication for the economy, but rather whether they have been altered to reflect a political agenda.

The Great Postal Boycott Must End. Inflation about to get insane.

The AI revolution is beginning to have a significant and disproportionate impact on entry-level workers in the American labor market.

To fend off the far right, democracy needs to deliver.

We have become an authoritarian state, and our top newsrooms are in denial. And soon we’ll be in a depression, and they will be in denial about that as well.

Splash

SpaceX bounces back with a Starship test flight that ended on a buoyant note.

Huh! I was told this rocket would never work. Never. That’s what all the good liberals said.

And that’s what they also said about SpaceX’s other rockets nearly a decade-and-a-half ago. Not a great track record, really. The funny part about doing hard things is they often fail a lot in the initial phases.

Get out there and build shit. Ignore the posers, losers, doubters and haters. That’s all you can really do.

The Dollheads – Burger King is Hiring

I don’t like this song for itself much, but from a nostalgic perspective I do. It reminds me of Riot Grrrl and when feminism was actually good. That’s back when we were all attempting to have fun, before identitarian BS took over and before men were treated like default rapists 100% of the time.

The song has all of two chords and is very repetitive, but in its own way it’s still fun. Though I won’t listen to it again.